An overview of the direct cyano-acylation/-esterification of unsaturated hydrocarbons

Document Type : Review Article

Authors

1 Professor, Pharmaceuticals and Chemistry, Faculty of Medicine, Alfraganus University, Tashkent, Uzbekistan

2 College of Medical Techniques, Al-Farahidi University, Baghdad, Iraq.

3 Webster University in Tashkent

4 Department of Biochemistry, Bukhara State Medical Institute, Bukhara, Uzbekistan

5 Associate professor, Kimyo international university in Tashkent , Shota Rustaveli street 156, 100121, Тashkent, Uzbekistan

6 Professor, Scientific and Practical Center of Immunology, Allergology and Human Genomics at Samarkand State Medical University, Samarkand, Uzbekistan

7 1. “Tashkent Institute of Irrigation and Agricultural Mechanization Engineers” National Research University, Tashkent, Uzbekistan 2. Western Caspian University, Scientific researcher, Baku, Azerbaijan

8 DSc, Professor, Head of the Department of Otorhinolaryngology, Faculty of Postgraduate Education, Samarkand State Medical University, Samarkand, Uzbekistan.

9 1. Associate Professor of the Department of Economic Theory, Candidate of Economic Sciences, Samarkand Institute of Economics and Service, Samarkand, Uzbekistan. 2. Baku Eurasian University, Baku, AZ 1073, Azerbaijan,

10 Assistant professor, Department of Agronomy, Navoi State University of Mining and Technology, Navoi, Uzbekistan

Abstract
This review aims to summarize the current literature on the direct vicinal cyano-acylation and cyano-esterification of unsaturated hydrocarbons, with a particular focus on the mechanistic features of these reactions. This review is structured into four main sections. The first section covers the cyano-acylation of alkenes, followed by a discussion of cyano-esterification of alkenes in the second section. The third section consists of an overview of cyano-acylation of alkynes, while the final section focuses on the cyano-esterification of alkynes.

Graphical Abstract

An overview of the direct cyano-acylation/-esterification of unsaturated hydrocarbons

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Volume 8, Issue 4 - Serial Number 4
July and August 2025
Pages 840-848

  • Receive Date 28 May 2025
  • Revise Date 25 June 2025
  • Accept Date 26 June 2025