Chemical Review and Letters

Advances in the formation and properties of nanofiber biomaterials from polyvinyl alcohol/carboxymethylcellulose/nanosilver systems for medical applications

Document Type : Review Article

Authors

Khaydar Ergashovich Yunusov 1
Mirafzal Muzaffar o`g`li Mirkholisov 1
Malika Askarovna Azizova 1
Javlon Zafar o`g`li Jalilov 1
Sardor Sobirjanovich Yarmatov 1
Jamoliddin Nasiriddinovich Todjiyev 2
Abdushkur Abdukhalilovich Sarimsakov 1
Abdumutolib Abdupatto o`g`li Atakhanov 1
Jiang Guohua 3
Aleksandr Alexandrovich Rogachev 4

1 Institute of Polymer Chemistry and Physics, Academy of Sciences of the Republic of Uzbekistan, 100128, str. A. Khadyri 7 “b”, Tashkent, Uzbekistan. E-mail: [email protected]

2 Department of Chemistry, National University of Uzbekistan named after Mirzo Ulugbek, 100174, Tashkent, Uzbekistan

3 College of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, 310018, China

4 Institute of New Materials Chemistry of the National Academy of Sciences of Belarus, 220141, Republic of Belarus, city Minsk, st. F. Skorina-36

https://doi.org/10.22034/crl.2024.473962.1409
Abstract
Poly (vinyl alcohol) (PVA) and sodium-carboxymethylcellulose (Na-CMC) are hydrophilic polymers with excellent biocompatibility and biodegradability and have been applied in various biomedical areas due to their favorable properties. Polyvinyl alcohol/sodium-carboxymethylcellulose composites have attracted considerable attention due to the synergistic relationship between the two polymers and the development of novel blends with improved properties. On the one hand, polyvinylalcohol is a versatile polymer with better mechanical properties than sodium-carboxymethylcellulose. On the other hand, sodium-carboxymethylcellulose has high biodegradability and biocompatibility but suffers from poor mechanical properties. This review highlights recent progress in the fabrication, properties, and potential applications of polyvinyl alcohol/sodium-carboxymethylcellulose/silver nanoparticles composites based on nanofibers in the fields of drug delivery, food packaging, and biomaterials for curing burns and wounds.

Graphical Abstract

Advances in the formation and properties of nanofiber biomaterials from polyvinyl alcohol/carboxymethylcellulose/nanosilver systems for medical applications

Keywords

Electrospinning
nanofiber mat
carboxymethylcellulose
polyvinyl alcohol
silver nanoparticles
wound heling

Subjects

  • Receive Date 19 August 2024
  • Revise Date 15 November 2024
  • Accept Date 22 November 2024

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