Chemical Review and Letters

Preparation of magnetic nanodendrimers and their applications in organic reactions and biomedicine: An update

Document Type : Review Article

Authors

Fatemeh Kalantari 1
Mohammad Reza Poor Heravi 2
Ali Ramazani 1
Rovnag Rzayev 3

1 1Department of Chemistry, Faculty of Science, University of Zanjan, Zanjan 45371-38791, Iran

2 2Department of Chemistry, Payame Noor University, PO Box 19395-3697, Tehran, Iran

3 Composite Materials Scientific Research Center of Azerbaijan State University of Economics (UNEC), 194 M.Mukhtarov str. Baku, Azerbaijan

https://doi.org/10.22034/crl.2024.464729.1364
Abstract
In this review, the bioactive agents can be encapsulated into the interior of the dendrimers or chemically grafted/physically adsorbed on the dendrimer surface with the option of tailoring the carrier to the fundamental needs of the active material and its therapeutic applications. However, the high density of exo-presented surface groups allowed attachment of targeting groups or functionality that could modify the solution behavior or toxicity of dendrimers. Quite remarkably, modified dendrimers were shown to act as nano-drugs against tumors, bacteria, and viruses. Also, it was applied in medicin and agents of contrast for MRI.

Graphical Abstract

Preparation of magnetic nanodendrimers and their applications in organic reactions and biomedicine: An update

Keywords

MNPs
PAMAM
Biomedicine
Dendrimer
Generation dendrimer

Subjects

Chemical Review and Letters
Volume 8, Issue 2 - Serial Number 2
Winter 2025
Pages 211-239

  • Receive Date 25 June 2024
  • Revise Date 07 September 2024
  • Accept Date 28 September 2024

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