Direct acyl-mono/-di/-tri-fluoromethylation of olefins: A review

Document Type : Review Article

Authors

1 School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan, China.

2 Department of Russian Language and Teaching Methods, National Pedagogical University of Uzbekistan, Tashkent, Uzbekistan.

3 Department of Language and Literature Education, University of Business and Science, Namangan, Uzbekistan.

4 Department of Psychology and Humanities, Economic and Pedagogical University, Karshi, Uzbekistan.

5 Department of Propedeutics of Children's Diseases, Samarkand State Medical University, Samarkand, Uzbekistan.

6 Bukhara Medical University, Bukhara, Uzbekistan.

7 Department of Natural Sciences, Termez University of Economics and Service, Termez, Uzbekistan.

8 Tashkent State Technical University named after Islam Karimov, Tashkent, Uzbekistan.

9 Department of Software Engineering, Andijan State University, Andijan, Uzbekistan.

10 Department of Biology, Bukhara State University, Bukhara, Uzbekistan.

Abstract
This review, which covers the literature from 2020 to 2025, aims to provide a thorough insight into the synthesis of β-mono-/di-/-tri-fluoromethylated carbonyl compounds via direct vicinal acyl-mono/-di/-tri-fluoromethylation of alkenes also highlighting their mechanistic accepts that may provide new insights into catalyst improvement and development.

Graphical Abstract

Direct acyl-mono/-di/-tri-fluoromethylation of olefins: A review

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Volume 9, Issue 2 - Serial Number 2
March and April 2026
Pages 269-278

  • Receive Date 30 September 2025
  • Revise Date 23 January 2026
  • Accept Date 24 January 2026