Direct 1,2-thiosulfonylation of alkenes: An overview

Document Type : Review Article

Authors

1 Nakhchivan State University, Faculty of Natural Sciences and Agriculture, Department of Chemistry, Republic of Azerbaijan, Nakhchivan Autonomous Republic, Nakhchivan city, AZ7000

2 Department of Orthopedic Dentistry. Faculty of Dentistry of the Samarkand State Medical University, Samarkand, Uzbekistan.

3 Department of Pharmaceuticals and Chemistry, Faculty of Medicine, Alfraganus University, Tashkent, Uzbekistan.

4 Department of Infectious Diseases and Infectious Diseases of Children, Bukhara State Medical Institute Named after Abu Ali Ibn Sino, Uzbekistan.

5 Faculty of Architecture and Construction, Department of Architecture and Computer Graphics, Fergana State Technical University, Fergana, Uzbekistan.

6 Faculty of Pedagogy and Social-Humanitarian Sciences, Interfaculty Department of Foreign Languages, Termez University of Economics and Service, Termez, Uzbekistan.

7 Department of Engineering Graphics and Design Theory, Tashkent Institute of Irrigation and Agricultural Mechanization Engineers, National Research University, Tashkent, Uzbekistan.

8 Azerbaijan State Oil and Industry University, Baku, Azerbaijan.

9 Scientific Research Center, Scientific Foundations and Problems of the Development of the Economy of Uzbekistan, Tashkent State University of Economics, Tashkent, Uzbekistan.

10 Samarkand State University Named After Sharof Rashidov, P. O. Box: 703004, Samarkand, Uzbekistan.

10.22034/crl.2025.537037.1663
Abstract
This review article aims to survey the literature on methodologies for the direct vicinal 1,2-thiosulfonylation of alkenes. This review is divided into two sections based on the type of thiosulfonylating reagents: the first covers the thiosulfonylation of alkenes using bifunctional reagents, while the second focuses on three-component reactions.

Graphical Abstract

Direct 1,2-thiosulfonylation of alkenes: An overview

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Volume 8, Issue 5 - Serial Number 5
September and October 2025
Pages 1093-1104

  • Receive Date 25 July 2025
  • Revise Date 15 September 2025
  • Accept Date 25 September 2025