[1] D.J. Newman, G.M. Cragg, Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019, J. Nat. Prod. 83 (2020) 770-803,
https://doi.org/10.1021/acs.jnatprod.9b01285.
[2] J. Gu, Y. Gui, L. Chen, G. Yuan, H.-Z. Lu, X. Xu, Use of natural products as chemical library for drug discovery and network pharmacology, PLos One 8 (2013) e62839. https://doi.org/10.1371/journal.pone.0062839.
[3] G.M. Cragg, D.J. Newman, Medicinals for the millennia: the historical record, Ann. NY Acad. Sci.
953 (2001) 3-25, https://doi.org/
10.1111/j.1749-6632.2001.tb11356.x
[4] WHO global report on traditional and complementary medicine 2019, Geneva: World Health Organization, (2019), ISBN 978-92-4-151543-6.
[5] (a) M.S. Aslam, M.S. Ahmed, Worldwide importance of medicinal plants: current and historical perspectives, Recent Adv. Biol. Med. 2 (2016) 88 -93, https://doi.org/10.18639/RABM.2016.02.338811.
(b) J. Yakubu, O.A. Sodipo, S.A. Umarfarouk, Phytochemical Profiling, Toxicity Study and Abortifacient Activity of Seed and Whole Plant of Momordica charantia Linn. (CUCURBITACEAE), Chem. Rev. Lett. 5 (2022) 200 -206.
https://doi.org/10.22034/CRL.2022.322197.1149
[6] State Pharmacopoeia Committee: Pharmacopoeia of the People’s Republic of China. Beijing: Medical Science and Technology Press, 22 (2012).
[7] X. Peigen, H. Liyi, W. Liwei, Ethnopharmacologic study of chinese rhubarb, J. Ethnopharmacol. 10 (1984) 275-293,
https://doi.org/10.1016/0378-8741(84)90016-3
[8] X.S. Fu, F. Cheng, X.H. Liu, H. Xu, Y.Z. Zhou, Progress in research of chemical constituents and pharmacological actions of Rhubarb, Chin. J. New Drugs 20 (2011) 1534-1539.
[9] H. Rehman, W. Begum, F. Anjum, H. Tabasum, Rheum emodi (Rhubarb): A fascinating herb, J. Pharmacog. Phytochem. 3 (2014) 89-94.
[10]M.B. Rokaya, Z. Münzbergová, B. Timsina, K.R. Bhattarai, Rheum australe D. Don: A review of its botany, ethnobotany, phytochemistry and pharmacology, J. Ethnopharmacol. 141 (2012) 761-74, https://doi.org/10.1016/j.jep.2012.03.048.
[11] National Pharmacopoeia Committee. Pharmacopoeia of Peoples Republic of China. Part 1. China Medical Science Press, (2020) 24-25.
[12] Analysis of Rhubarb and the Yew. The Philosophical Magazine 26 (1829), 151-152.
[13]Y.J. Cao, Z.J. Pu, Y.P. Tang, J. Shen, Y.-Y. Chen, A. Kang, G.-S. Zhou, J.-A. Duan, Advances in bio-active constituents, pharmacology and clinical applications of rhubarb, Chin. Med. 12 (2017) Article no 36,
https://doi.org/10.1186/s13020-017-0158-5.
[14]
K. Komatsu,
Y. Nagayama,
K. Tanaka,
Y. Ling, S.Q.
Cai,
T. Omote,
M. R. Meselhy, Comparative study of chemical constituents of Rhubarb from different origins, Chem. Pharm.Bull. 54(2006)1491- 1499.
[15] T. Liu, M. Yu, Y. Dai, Y. Xiao, L. Li, Traditional method of rhubarb processing optimized by combining flavour analysis with anthraquinone content determination, Front. Nutr. 11 (2024) 1406430.
[16]D.Luo,M.He, J.Li, H.Du, Q. Mao, N. Pei, G.Zhong, H. Ouyang, S. Yang, Y.Feng, Integrating the rapid constituent profiling strategy and multivariate statistical analysis for herb ingredients research, with Chinese official rhubarb and Tibetan rhubarb as an example, Arabian. J. Chem. 14 (2021) 103269.
[17]J. He, J. Sun, L. Liang Wang, Y. Luo, W. Gao, H. Guo, H. Zhao, Chemistry, pharmacology and processing method of rhubarb (Rheum species): a review, J. Food Bioactives 8 (2019) 42-50.
[18] Q. Huang, G. Lu, H.-M. Shen, M.C.M. Chung, C.N. Ong, Anti-cancer properties of anthraquinones from rhubarb, Med. Res. Rev. 27 (2007) 609-630,
https://doi.org/10.1002/med.20094.
[19] M. Stompor-Goracy, The health benefits of emodin, a natural anthraquinone derived from rhubarb- a summary update, Int. J. Mol. Sci. 22 (2021) 9522, https://doi.org/10.3390/ijms22179522.
[20] L. Xie, H. Tang, J. Song, J. L. Long, Zhang, X. Li, Chrysophanol: a review of its pharmacology, toxicity and pharmacokinetics, J. Phar. Pharmacol. 71 (2019) 1475-1487, https://doi.org/10.1111/jphp.13143.
[21] J. He, J. Sun, L. Liang Wang, Y. Luo, W. Gao, H. Guo, H. Zhao, Chemistry, pharmacology and processing method of rhubarb (Rheum species): a review, J. Food Bioactives 8 (2019) 42-50.
[22] Y. Hu, W. Huang, Y. Luo, L. Xiang, J. Wu, Y. Zhang, Y. Zeng, C. Xu, X. Meng, P. Wang, Assessment of the anti-inflammatory effects of three rhubarb anthraquinones in LPS-Stimulated RAW264.7 macrophages using a pharmacodynamic model and evaluation of the structure-activity relationships, J. Ethnopharmacol. 273 (2021); 114027,
https://doi.org/10.1016/j.jep.2021.114027.
[23]E.M. Malik, C.E. Muller, Anthraquinones as pharmacological tools and drugs, Med. Res. Rev. 6 (2016) 705-748. https://doi.org/10.1002/med.21391.
[24]A. Espinosa, G.P.-Y. Mino-C, Y. Ma H. Santos, M. Nadeau, N.P. Seeram, D.C. Rowley, Anti-amebic effects of Chinese rhubarb (
Rheum palmatum) leaves' extract, the anthraquinone rhein and related compounds, Heliyon 6 (2020) e03693,
https://doi.org/10.1016/j.heliyon.2020.e03693.
[25]A.K. Khattak, S.M. Hassan, S.S. Mughal, General overview of phytochemistry and pharmacological potential of
Rheum palmatum (Chinese rhubarb), Innovare J. Ayur. Sci. 6 (2020) 5 - 9,
https://doi.org/10.22159/ijas.2020.v8i6.39192.
[26]P. Li, Q.Lu, W. Jiang, X. Pei, Y. Sun, H.Hao, K.Hao, Pharmacokinetics and Pharmacodynamics of rhubarb anthraquinones extract in normal and disease rats, Biomed. Pharmacother. 91 (2017) 425- 435, https://doi.org/10.1016/j.biopha.2017.04.109.
[27]D. Yixuan, Analysis of Rhubarb's Pharmacological Action and Clinical Application, MEDS Chin. Med. 3 (2021) 21-24.
[28]W. Huang, Y. rao, L.Li, Y. An, Clinical effect of rhubarb on the treatment of chronic renal failure : A meta-analysis, Front. Pharmacol. 14 (2023) 1108861.
http://doi.org/10.3389/fphar.2023.1108861
[29] J. Kolodziejczyk-Czepas, O. Liudvytska,
Rheum rhaponticum and
Rheum rhabarbarum: a review of phytochemistry, biological activities and therapeutic potential.
Phytochem Rev 20, 589 - 607 (2021).
[30] B. A. Zargar , M. H. Masoodi , B. Ahmed , S. A. Ganie, Phytoconstituents and therapeutic uses of
Rheum emodi wall. ex Meissn, Food Chem. 128 (2011)585-589.
https://doi.org/10.1016/j.foodchem.2011.03.083
[31] J.-L. Kan, Y.-P. Ruan, Z.-J. Mao, L.-Y. You, Z. Chen, Q-marker prediction analysis of rhubarb in
Fengyin decoction based on fingerprint and network pharmacology, Nat. Prod. Commun. 16 (2021) 1-10.
https://doi.org/10.1177/1934578X211038792.
[32] L. Chen Sun, H. Yuan, A. Wu, J. Lu, S. Ma, A holistic strategy for quality and safety control of traditional Chinese medicines by the “iVarious” standard system, J. Pharm. Anal. 7 (2017) 271-279.
https://doi.org/10.1016/j.jpha.2017.07.008.
[33] G. Indrayanto, Recent development of quality control methods for herbal derived drug preparations, Nat. Prod. Commun. 13 (2018) 1599 -1606. https://doi.org/
10.1177/1934578X1801301208.
[36] (a) T.T.D. Au, Y.L. Ho, Y.S. Chang, Qualitative and quantitative analysis methods for quality control of rhubarb in Taiwan’s markets, Front. Pharmacol. 15 (2024), Article No. 1364460. http://doi.org/10.3389/fphar.2024.1364460
(b) F.Y. Maleki, M.Payab, A. Baghban, H. Shiekhloie, Determination of Fenvalerate reside in raisin via vortex-assisted surfactant-enhanced emulsification liquid–liquid microextraction (VSLLME) method by using HPLC system, Chem. Rev. Lett. 3 (2020) 161-167.
https://doi.org/10.22034/CRL.2020.233886.1064
[37] P. Singh, J. Negi, G. Pant, HPLC separation of anthraquinones from rhubarbs. Int. J. Med. Aromatic Plants 2 (2012) 531-535.
[38] H.-X. Zhang, M.-C. Liu, Separation procedures for the pharmacologically active components of rhubarb. J. Chromatogr. B 812 (2004) 175-181. https://doi.org/10.1016/j.jchromb.2004.08.010
[39] H. Xiang, J. Zuo, F. Guo, D. Dong, What we already know about rhubarb: a comprehensive review. Chin. Med. 15 (2020) 88,
https://doi.org/10.1186/s13020-020-00370-6.
[41] F. Loschi, M. Faggian, S. Sut, I. Ferrarese, E. Maccari, G. Peron, S. Dall'Acqua, Development of an LC-DAD-MS-based method for the analysis of hydroxyanthracene derivatives in food supplements and plant materials, Molecules 27 (2022) 1932.
https://doi.org/10.3390/molecules27061932
[42]T. Zhu, X. Liu, X. Wang, G. Cao, K. Qin, K. Pei, H. Zhu, H. Cai, M. Niu, B. Cai, Profiling and analysis of multiple compounds in rhubarb decoction after processing by wine steaming using UHPLC–Q-TOF-MS coupled with multiple statistical strategies, J. Sep. Sci. 39 (2016) 3081- 3090.
https://doi.org/10.1002/jssc.201600256
[43] P.P. Rai, M. Shok, Thin layer chromatography of hydroxyanthraquinones in plant extract, Chromatographia 14 (1981) 599-600, https://doi.org/10.1007/bf02262892.
[44] K. Danielsen, G.W. Francis, An alternative solvent system for the separation of anthraquinone aglycones from rhubarb on silica thin layers, Chromatographia 38 (1994) 520.
https://doi.org/10.1007/BF02269846.
[45] X.P. Wang, M.X. Ma, F.M. Shuang, Y. Zhang, J.H.Pan, Determination of formation constants for the inclusion complexes between emodin, aloe-emodin and cyclodextrins by thin layer chromatography, Chin. J. Anal. Chem. 30 (2002) 38-41.
[46] N.P. Singh, A.P. Gupta, A.K. Sinha, P.S. Ahuja, High-performance thin layer chromatography method for quantitative determination of four major anthraquinone derivatives in Rheum emodi, J. Chromatogr. A 1077 (2005) 202-206, https://doi.org/10.1016/j.chroma.2005.03.130.
[48] Y. Ge, M. Sun, L.F. Salome-Abarca, M. Wang, Y.H. Choi, Investigation of species and environmental effects on rhubarb roots metabolome using
1H NMR combined with high performance thin layer chromatography, Metabolomics 14 (2018) 137,
https://doi.org/10.1007/s11306-018-1421-1.
[49] Y. Ohshima, Y. Ohno, K. Kajiyama, K. Takahashi, High-perforformance liquid chromatographic separation of rhubarb constituents, J. Chromatogr. 360 (1986) 303-306,
https://doi.org/10.1016/S0021-9673(00)91680-7.
[50] Y Kashiwada, G. Nonaka, I. Nishioka, Studies on rhubarb (Rhei Rhizoma). XV. Simultaneous determination of phenolic constituents by high-performance liquid chromatography, Chem. Pharm. Bull. 37 (1989) 999 -1004,
https://doi.org/10.1248/cpb.37.999.
[51] Dj Djozan, Y. Assadi, Determination of anthraquinones in rhubarb roots, dock flowers and senna leaves by normal-phase high performance liquid chromatography, Talanta 42 (1995) 861 – 865,
https://doi.org/10.1016/0039-9140(95)01500-B.
[52] K. Komatsu, Y. Nagayama, K. Tanaka, Y. Ling, P. Basnet, M.R. Meselhy, Development of a high herformance liquid chromatographic method for systematic quantitative analysis of chemical constituents in rhubarb, Chem. Pharm. Bull. 54 (2006) 941 – 948,
https://doi.org/10.1248/cpb.54.941.
[53] M. Ding, S Ma, D Liu, Simultaneous determination of hydroxyanthraquinones in rhubarb and experimental animal bodies by high-performance liquid chromatography, Anal. Sci. 19 (2003) 1163 -1165, https://doi.org/
10.2116/analsci.19.1163.
[54] X.-Y. Gao, Y. Jiang, J.-Q. Lu, P.-F. Tu, One single standard substance for the determination of multiple anthraquinone derivatives in rhubarb using high-performance liquid chromatography-diode array detection, J. Chromatogr. A 1216 (2009) 2118 – 2123,
https://doi.org/10.1016/j.chroma.2008.11.104.
[55] C.-L. Liu, P.-L. Zhu, M.-C. Liu, Computer-aided development of a high-performance liquid chromatographic method for the determination of hydroxyanthraquinone derivatives in Chinese herb medicine rhubarb, J. Chromatogr. A 857 (1999) 167-174,
https://doi.org/10.1016/S0021-9673(99)00771-2.
[56] X. Su, L. Kong, X. Li, X. Chen, M. Guo, H. Zou, Biological Fingerprinting Analysis by Liquid Chromatography/Mass Spectrometry for Evaluation of DNA Structural Selectivity of Multiple Compounds in Natural Products, J. Comb. Chem. 8 (2006) 544 -550, https://doi.org/10.1021/cc060039l.
[57] S.-X. Feng, M.-M. Li, D. Zhao, X.-H. Li, L. Zhang, Z. Wang, N.-N. Gao, Simultaneous determination of 10 anthraquinones in rhubarb based on HPLC-Q-HR/MS, Chin. Herbal Med. 9 (2017) 388 – 395, https://doi.org/10.1016/S1674-6384(17)60120-5.
[58] M.-R. S. Fuh, H.-J. Lin, Analysis of rhubarb by liquid chromatography- electrospray-mass spectrometry, Tamkang J. Sci. Engineering 6 (2003) 31-36.
[59] M. Ye, J. Han, H. Chen, J. Zheng, D. Guo, Analysis of phenolic compounds in rhubarbs using liquid chromatography coupled with electrospray ionization mass spectrometry, J. Am. Soc. Mass. Spectrom. 18 (2007) 82-91, https://doi.org/10.1016/j.jasms.2006.08.009.
[60] C.-C. Lin, C.-I. Wu, T.-C. Lin, S.-J. Sheu. Determination of 19 rhubarb constituents by high performance liquid chromatography–ultraviolet–mass spectrometry, J. Sep. Sci. 29 (2006) 2584 -2593. https://doi.org/10.1016/j.jasms.2006.08.009.
[61] W. Jin, Y.-F. Wang, R.-L. Ge, H.-M. Shi, C.-Q. Jia, Tu P-F. Simultaneous analysis of multiple bioactive constituents in Rheum tanguticum Maxim. ex Balf. by high-performance liquid chromatography coupled to tandem mass spectrometry, Rapid Commun. Mass Spectrom. 21 (2007) 2351-2360, https://doi.org/10.1002/rcm.3086.
[62] S.-Y. Wei, W.-X. Yao, W.-Y. Ji, J.-Q. Wei, S.-Q. Peng. Qualitative and quantitative analysis of anthraquinones in rhubarbs by high performance liquid chromatography with diode array detector and mass spectrometry, Food Chem. 141 (2013) 1710-1715.
https://doi.org/10.1016/j.foodchem.2013.04.074
[63] D. He, B. Bo Chen, Q. Tian, S. Yao, Simultaneous determination of five anthraquinones in medicinal plants and pharmaceutical preparations by HPLC with fluorescence detection, J. Pharm. Biomed. Anal. 49 (2009)1123-1127, https://doi.org/10.1016/j.jpba.2009.02.014.
[64] W.-C. Weng, S.-J. Sheu. Separation of anthraquinones by capillary electrophoresis and high-performance liquid chromatography, J. High Resol. Chromatogr. 23 (2000) 143-148,
https://doi.org/10.1002/(SICI)1521-4168 (20000201)23:2<143::AID-JHRC143>3.0.CO;2-U
[65] J. Koyama, I. Morita, N. Kobayashi, Simultaneous determination of anthraquinones in rhubarb by high-performance liquid chromatography and capillary electrophoresis, J. Chromatogr. A 1145 (2007): 183-189,
https://doi.org/10.1016/j.chroma.2007.01.076.
[66] W. Jin, R. Ge, Q. Wei, T. Bao, H. Shi, P. Tu, Development of high-performance liquid chromatographic fingerprint for the quality control of
Rheum tanguticum Maxim. ex Balf., J. Chromatogr. A. 1132 (2006) 320-324,
https://doi.org/10.1016/j.chroma.2006.08.022.
[67] X.-H. Fan, Y.-Y. Cheng, Z.-L. Ye, R.-C. Lin, Z.-Z. Qian, Multiple chromatographic fingerprinting and its application to the quality control of herbal medicines, Anal. Chim. Acta 555 (2006) 217 -224.,
https://doi.org/10.1016/j.aca.2005.09.037.
[68] M. Sun, H. Wu, M. He, Y. Jai, L. Wang, T. Liu, L. Hui, L. Li, S. Wei, E.V. Wijk, R.V. Wijk, K.W.-K. Tsim, C. Li, M. Wang, Integrated assessment of medicinal rhubarb by combination of delayed luminescence and HPLC fngerprint with emphasized on bioactivities based quality control, Chin. Med. 15 (2020) 72,
https://doi.org/10.1186/s13020-020-00352-8.
[69] S. Xiaoyu, Y. Zhuobin, Determination of active components in rhubarb by cyclodextrin-modified capillary zone electrophoresis, Sensors 1 (2001) 229-235,
https://doi.org/10.3390/s10700229.
[70] F. Fei Li, Q.-E. Cao, Z. Ding, Separation and determination of five anthraquinones in rheum and rheum-containing preparations by capillary zone electrophoresis, Chromatographia 59 (2004) 753 – 757, https://doi.org/10.1365/s10337-004-0314-9.
[71] Y. Li, H. Liu, X. Ji, J. Li, Optimized separation of pharmacologically active anthraquinones in rhubarb by capillary electrochromatography, Electrophoresis 21 (2000) 3109-3115, https://doi.org/
10.1002/1522-2683(20000901)21:15<3109::AID-ELPS3109>3.0.CO;2-Q
[72] H. Lu, J. Wang, X. Wang, X. Lin, X. Wu, Z. Xie, Rapid separation and determination of structurally related anthraquinones in Rhubarb by pressurized capillary electrochromatography, J. Pharm. Biomed. Anal. 43 (2007) 352-357,
https://doi.org/10.1016/j.jpba.2006.06.023
[73] X. Shang, Z. Yuan. Determination of six components in Rhubarb by cyclodextrin-modified micellar electrokinetic chromatography using a mixed micellar system of sodium cholate and sodium taurocholate, Anal. Chim. Acta. 456 (2002) 183-188,
https://doi.org/10.1016/S0003-2670(02)00044-2.
[74] G. Li, X. Chen, M. Liu, Z. Hu, Separation and identification of active components in the extract of Rheum natural products by microemulsion electrokinetic chromatography, Analyst 123 (1998) 1501-1505, https://doi.org/
10.1039/A800353.
[75]J. Wang, H. Li, C. Jin, Y. Qua, X. Xiao, Development and validation of a UPLC method for quality control of rhubarb-based medicine: Fast simultaneous determination of five anthraquinone derivatives, J. Pharm. Biomed. Anal. 47 (2008) 765-770, https://doi.org/10.1016/j.jpba.2008.03.011.
[76]L.L. Gao, T. Guo, X.D. Xu, J.S. Yang, Rapid identifcation and simultaneous analysis of multiple constituents from Rheum tanguticum Maxim. ex Balf by UPLC/Q-TOF-MS, Nat. Prod. Res. 31 (2017)1529-1535. https://doi.org/10.1080/14786419.2017.1280491.
[77]Z. Wang, D. Wang, S. Zheng, L. Wu, L. Huang, S. Chen, Ultra-performance liquid chromatography-quadrupole\time-of- fight mass spectrometry with multivariate statistical analysis for exploring potential chemical markers to distinguish between raw and processed
Rheum palmatum, BMC Complem. Altern. M. 14 (2014) 302,
https://doi.org/10.1186/1472-6882-14-302.
[78]W. Cao, L. Yi, L.H. Ye, J. Cao, S.S. Hu, J.J. Xu, L.Q. Peng, Q.Y. Zhu, Q.Y. Zhang, Application of a highly sensitive magnetic solid phase extraction for phytochemical compounds in medicinal plant and biological fluids by ultra-high performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry, Electropharesis 36 (2015) 2404-2412,
https://doi.org/10.1002/elps.201500151.
[79]D.Z. Yang, G. Sun, A.H. Zhang, S. Fu, J.H. Liu, Screening and analyzing the potential bioactive components from rhubarb, using a multivariate data processing approach and ultra-high performance liquid chromatography coupled with time-of-fight mass spectrometry, Anal. Methods 7 (2015) 650-661. https://doi.org/10.1039/c4ay02506g.
[80]A. Chen, L. Sun, H. Yuan, A. Wu, J. Lu, S. Ma, Simultaneous qualitative and quantitative analysis of 11 active compounds in rhubarb using two reference substances by UHPLC, J. Sep. Sci. 41 (2018) 3686-3696. https://doi.org/
10.1002/jssc.201800479.
[81]W. Stensen, E. Jensen, High-performance liquid chromatographic separations of naphthoquinones and their derivatives: Effect of hydrogen bonding on retention, J. Chromatogr. A 659(1994) 87-93.
https://doi.org/10.1016/0021-9673(94)85009-7.
[82] N. Sethi, A. Anand, A. Sharma, K.K. Chandrul, G. Jain, K.S. Srinivasa, High speed counter-current chromatography: a support-free LC technique, J. Pharm. Bioall. Sci. 1 (2009) 8-15.
https://doi.org/10.4103/0975-7406.62680.
[83]T.U. Zhang, L.K. Pannell, Q.-L.Pu, D.-G Cai, Y.Ito, Separation of hydroxyanthraquinone derivatives extracted from rheum with analytical high-speed counter current chromatography, J. Chromatogr.442 (1988) 455-458.
[84] F. Yang, T. Zhang, G. Tian, H. Cao, Q. Liu, Y. Ito, Preparative isolation and purification of hydroxyanthraquinones from
Rheum officinale Baill by high-speed counter-current chromatography using pH-modulated stepwise elution, J. Chromatogr. A 858 (1999) 103-107.
https://doi.org/10.1016/S0021-9673(99)00827-4.
[85]Y.Wei, T. Zhang, Y. Ito, Preparative separation of rhein from Chinese traditional herb by repeated high-speed counter-current chromatography, J. Chromatogr. A 1017 (2003) 125-130,
https://doi.org/10.1016/j.chroma.2003.08.015.
[86] R. Liu, A. Li, A. Sun, Preparative isolation and purification of hydroxyanthraquinones and cinnamic acid from the Chinese medicinal herb Rheum officinale Baill. by high-speed counter-current chromatography, J. Chromatogr. A 1052 (2004) 217-221, https://doi.org/10.1016/j.chroma.2004.08.101.
[87] B. Ma, J. Wang, C.-M. Liu, Q. Wang, Isolation and purification of seven compounds from extract of Rheum palmatum L. by high speed counter current chromatography and rapid preparative chromatography, J. Liq. Chromatogr. Rel. Tech. 37 (2014) 2546-2557. https://doi.org/ 10.1080/10826076.2013.850724.
[88] D. Aichner, M.Ganzera, Analysis of anthraquinones in rhubarb (
Rheum palmatum and
rheum officinale) by supercritical fluid chromatography, Talanta 144 (2015) 1239 - 1244.
https://doi.org/10.1016/j.talanta.2015.08.011.
[89] Y. Hong, L. Chen, Extraction of anthraquinones from rhubarb by molecularity imprinted-Matrix solid-phase dispersion method with HPLC detection, Anal. Lett. 46(2013) 2235 - 2252. https://doi.org/10.1080/00032719.2013.798797.