Chemical Review and Letters

Nano-assisted Detection of SARS-CoV-2: Recent Advances and Future Directions

Document Type : Review Article

Authors

Somayeh Jafarinejad 1
Arafeh Bigdeli 2
Bita Mehravi 3
Angila Ataei 4
Alireza Tabibzadeh 5
Omid Pourdakan 3
Alireza Ghasempour 3
Parsa Panahi 6

1 Finetech In Medicine Research Center, Iran. University of Medical Sciences, Tehran, Iran.

2 Department of Chemistry, Sharif University of Technology, Tehran, 11155-9516, Iran

3 Department of Medical Nanotechnology, Faculty of Advanced Technologies in Medicine, Iran. University of Medical Sciences, Tehran, Iran.

4 Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

5 Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran

6 Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

https://doi.org/10.22034/crl.2023.413575.1240
Abstract
In December 2019, an infectious respiratory disease caused by a new severe acute respiratory syndrome-related coronavirus (SARS-CoV-2), was reported in the city of Wuhan in China. Due to its fast expansion, the so-called “COVID-19” disease rapidly turned into a global pandemic and brought unprecedented challenges for the global community. Since its declaration by the world health organization (WHO) in February 2020, all healthcare professionals throughout the world have been trying to mitigate the spread of this virus and manage this disaster. Amongst various ongoing efforts, early detection of this virus and diagnosis of individuals and groups whom are infected with SARS-CoV-2 are pivotal steps that should be accomplished in the earliest possible moment. Nanostructures which are often used for targeting specific biological markers, can be considered as potential candidates for rapid detection of SARS-CoV-2, especially when fast, portable, easy-to-use, and accurate in-field detection kits are required. In this Review, we have summarized recent advances in the detection of coronaviruses in which nanostructures have been utilized to either generate or amplify the detection signal. Potential benefits of implementing nanostructures in the detection of SARS-CoV-2 has also been demonstrated. The applicability of coupling current detection methods with smartphone-based platforms, array-based sensing systems, wearable gadgets and other future directions of SARS-CoV-2 detection techniques have been further discussed.

Keywords

Nanostructures
Sensors
Early detection
Coronaviruses
SARS-CoV-2
Global pandemic
Virus Infection

Subjects

  1. M. Lai, D. Cavanagh, The molecular biology of coronaviruses, Advances in virus research, Elsevier1997, pp. 1-100.
  2. A. Wevers, L. van der Hoek, Clinics in laboratory medicine, 29 (2009) 715-724.
  3. Su, G. Wong, W. Shi, J. Liu, A.C. Lai, J. Zhou, W. Liu, Y. Bi, G.F. Gao, Trends in microbiology, 24 (2016) 490-502.
  4. Forni, R. Cagliani, M. Clerici, M. Sironi, Trends in microbiology, 25 (2017) 35-48.
  5. Zhong, B. Zheng, Y. Li, L. Poon, Z. Xie, K. Chan, P. Li, S. Tan, Q. Chang, J. Xie, The Lancet, 362 (2003) 1353-1358.
  6. B. Reusken, B.L. Haagmans, M.A. Müller, C. Gutierrez, G.-J. Godeke, B. Meyer, D. Muth, V.S. Raj, L. Smits-De Vries, V.M. Corman, The Lancet infectious diseases, 13 (2013) 859-866.
  7. Lu, C.W. Stratton, Y.W. Tang, Journal of Medical Virology.
  8. Deutsche Apotheker Zeitung, 160 (2020).
  9. F.-W. Chan, K.-H. Kok, Z. Zhu, H. Chu, K.K.-W. To, S. Yuan, K.-Y. Yuen, Emerging Microbes & Infections, 9 (2020) 221-236.
  10. Liu, X. Xiao, X. Wei, J. Li, J. Yang, H. Tan, J. Zhu, Q. Zhang, J. Wu, L. Liu, J Med Virol, (2020).
  11. Zhou, X.-L. Yang, X.-G. Wang, B. Hu, L. Zhang, W. Zhang, H.-R. Si, Y. Zhu, B. Li, C.-L. Huang, Nature, 579 (2020) 270-273.
  12. Zhang, Q. Wu, Z. Zhang, Current Biology, (2020).
  13. S. Jones, New England Journal of Medicine, (2020).
  14. K. Mehta, G.M. Lyon, J.B. Varkey, The New England journal of medicine, 372 (2015) 1674-1674.
  15. H. Organization, (2020).
  16. Liu, A.A. Gayle, A. Wilder-Smith, J. Rocklöv, Journal of travel medicine, (2020).
  17. Remuzzi, G. Remuzzi, The Lancet, (2020).
  18. M. Arabi, S. Murthy, S. Webb, Intensive care medicine, (2020) 1-4.
  19. Casadevall, L.-a. Pirofski, The Journal of clinical investigation, 130 (2020).
  20. -Y. Zheng, Y.-T. Ma, J.-Y. Zhang, X. Xie, Nature Reviews Cardiology, (2020) 1-2.
  21. Udugama, P. Kadhiresan, H.N. Kozlowski, A. Malekjahani, M. Osborne, V.Y. Li, H. Chen, S. Mubareka, J. Gubbay, W.C. Chan, ACS nano, (2020).
  22. Zhou, S.-M. Dai, Q. Tong, Journal of Antimicrobial Chemotherapy, (2020).
  23. Li, M. Geng, Y. Peng, L. Meng, S. Lu, Journal of Pharmaceutical Analysis, (2020).
  24. Lu, Y. Shi, Journal of medical virology, (2020).
  25. Wu, J. Liu, X. Zhao, C. Liu, W. Wang, D. Wang, W. Xu, C. Zhang, J. Yu, B. Jiang, Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, (2020).
  26. Fang, G. Karakiulakis, M. Roth, The Lancet. Respiratory Medicine, (2020).
  27. Gurwitz, Drug development research, (2020).
  28. B. Patel, A. Verma, JAMA, (2020).
  29. M. Azar, M.L. Landry, Journal of clinical microbiology, 56 (2018).
  30. Bhadra, Y.S. Jiang, M.R. Kumar, R.F. Johnson, L.E. Hensley, A.D. Ellington, PloS one, 10 (2015) e0123126.
  31. F.-W. Chan, G.K.-Y. Choi, A.K.-L. Tsang, K.-M. Tee, H.-Y. Lam, C.C.-Y. Yip, K.K.-W. To, V.C.-C. Cheng, M.-L. Yeung, S.K.-P. Lau, P.C.-Y. Woo, K.-H. Chan, B.S.-F. Tang, K.-Y. Yuen, Journal of clinical microbiology, 53 (2015) 2722-2726.
  32. Lu, B. Whitaker, S.K. Sakthivel, S. Kamili, L.E. Rose, L. Lowe, E. Mohareb, E.M. Elassal, T. Al-sanouri, A. Haddadin, D.D. Erdman, Journal of clinical microbiology, 52 (2014) 67-75.
  33. Shirato, T. Yano, S. Senba, S. Akachi, T. Kobayashi, T. Nishinaka, T. Notomi, S. Matsuyama, Virology journal, 11 (2014) 139.
  34. S. Hui, E. I Azhar, T.A. Madani, F. Ntoumi, R. Kock, O. Dar, G. Ippolito, T.D. Mchugh, Z.A. Memish, C. Drosten, International Journal of Infectious Diseases, 91 (2020) 264-266.
  35. Xiao, X. Liu, J. Ji, M. Li, J. Li, L. Yang, W. Sun, P. Ren, G. Yang, J. Zhao, bioRxiv, (2020).
  36. M. Corman, O. Landt, M. Kaiser, R. Molenkamp, A. Meijer, D.K. Chu, T. Bleicker, S. Brünink, J. Schneider, M.L. Schmidt, Eurosurveillance, 25 (2020) 2000045.
  37. Zhou, C. Niu, Q. Wang, Y. Pan, X. Wang, M. Liu, X. Dai, medRxiv, (2020).
  38. Yelin, N. Aharony, E. Shaer-Tamar, A. Argoetti, E. Messer, D. Berenbaum, E. Shafran, A. Kuzli, N. Gandali, T. Hashimshony, Y. Mandel-Gutfreund, M. Halberthal, Y. Geffen, M. Szwarcwort-Cohen, R. Kishony, medRxiv, (2020) 2020.2003.2026.20039438.
  39. M. Casto, M.-L. Huang, A. Nalla, G.A. Perchetti, R. Sampoleo, L. Shrestha, Y. Wei, H. Zhu, A.L. Greninger, K.R. Jerome, medRxiv, (2020).
  40. Amanat, T. Nguyen, V. Chromikova, S. Strohmeier, D. Stadlbauer, A. Javier, K. Jiang, G. Asthagiri-Arunkumar, J. Polanco, M. Bermudez-Gonzalez, medRxiv, (2020).
  41. Liu, L. Liu, G. Kou, Y. Zheng, Y. Ding, W. Ni, Q. Wang, L. Tan, W. Wu, S. Tang, medRxiv, (2020).
  42. Wang, H. Li, J. Li, C. Yang, X. Guo, Z. Hu, Z. Chen, S. Wang, J. Liu, medRxiv, (2020) 2020.2003.2022.20041285.
  43. Lv, N.C. Wu, O.T.-Y. Tsang, M. Yuan, R.A. Perera, W.S. Leung, R.T. So, J.M.C. Chan, G.K. Yip, T.S.H. Chik, bioRxiv, (2020).
  44. Pan, X. Li, G. Yang, J. Fan, Y. Tang, J. Zhao, X. Long, S. Guo, Z. Zhao, Y. Liu, medRxiv, (2020).
  45. A. Costello, J.K. Millet, C.-Y. Hsia, G.R. Whittaker, S. Daniel, Biomaterials, 34 (2013) 7895-7904.
  46. Chen, K.-H. Chan, C. Hong, Y. Kang, S. Ge, H. Chen, E. Wong, S. Joseph, N.G. Patteril, U. Wernery, The Journal of infection, 73 (2016) 82-84.
  47. K. Chu, Y. Pan, S.M. Cheng, K.P. Hui, P. Krishnan, Y. Liu, D.Y. Ng, C.K. Wan, P. Yang, Q. Wang, Clinical chemistry, 66 (2020) 549-555.
  48. M. Corman, I. Eckerle, T. Bleicker, A. Zaki, O. Landt, M. Eschbach-Bludau, S. van Boheemen, R. Gopal, M. Ballhause, T.M. Bestebroer, D. Muth, M.A. Muller, J.F. Drexler, M. Zambon, A.D. Osterhaus, R.M. Fouchier, C. Drosten, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 17 (2012).
  49. Nao, K. Shirato, H. Katano, S. Matsuyama, M. Takeda, 2020.
  50. Li, M. Hong, B. Qiu, Z. Lin, Z. Cai, Y. Chen, G. Chen, Chemical Communications, 49 (2013) 10563-10565.
  51. F.-W. Chan, S. Yuan, K.-H. Kok, K.K.-W. To, H. Chu, J. Yang, F. Xing, J. Liu, C.C.-Y. Yip, R.W.-S. Poon, The Lancet, 395 (2020) 514-523.
  52. Huang, Y. Wang, X. Li, L. Ren, J. Zhao, Y. Hu, L. Zhang, G. Fan, J. Xu, X. Gu, The Lancet, 395 (2020) 497-506.
  53. Prakashan, N.S. Shrikrishna, M. Byakodi, K. Nagamani, S. Gandhi, Journal of Medical Virology, 95 (2023) e28416.
  54. Luo, M. Zhou, C. Fan, Y. Song, L. Wang, T. Xu, X. Zhang, Analytical Chemistry, 95 (2023) 5316-5322.
  55. O. Soh, B.C. Park, H.S. Park, M.S. Kim, H.E. Fu, Y.K. Kim, J.H. Lee, ACS sensors, 8 (2023) 839-847.
  56. -M. Gu, P.-C. Guan, S.-S. Xu, H.-M. Li, Y.-C. Kou, X.-D. Lin, M. Kathiresan, Y. Song, Y.-J. Zhang, S.-Z. Jin, The Journal of Chemical Physics, 158 (2023) 024203.
  57. Martínez‐Paredes, M.B. González‐García, A. Costa‐García, Electroanalysis: An International Journal Devoted to Fundamental and Practical Aspects of Electroanalysis, 21 (2009) 379-385.
  58. A. Layqah, S. Eissa, Microchimica Acta, 186 (2019) 224.
  59. Li, M. Hong, Y. Lin, Q. Bin, Z. Lin, Z. Cai, G. Chen, Chemical Communications, 48 (2012) 6562-6564.
  60. Kim, M. Park, J. Hwang, J.H. Kim, D.-R. Chung, K.-s. Lee, M. Kang, ACS sensors, 4 (2019) 1306-1312.
  61. Kim, J. Hwang, J.H. Kim, S. Lee, M. Kang, 2019 IEEE 14th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), IEEE2019, pp. 498-501.
  62. Guo, Y. Chen, Y. Jiang, H. Ju, Chemistry–A European Journal, 23 (2017) 9332-9337.
  63. Teengam, W. Siangproh, A. Tuantranont, T. Vilaivan, O. Chailapakul, C.S. Henry, Analytical chemistry, 89 (2017) 5428-5435.
  64. Kilianski, A. Mielech, X. Deng, S.C. Baker, Journal of Virology, (2013) JVI. 02105-02113.
  65. Qi, J.-Z. Duan, Z.-H. Wang, Y.-Y. Chen, P.-H. Zhang, L. Zhan, X.-Y. Yan, W.-C. Cao, G. Jin, Biomedical microdevices, 8 (2006) 247-253.
  66. N. Ishikawa, H.-K. Chang, M. Curreli, H.-I. Liao, C.A. Olson, P.-C. Chen, R. Zhang, R.W. Roberts, R. Sun, R.J. Cote, Acs Nano, 3 (2009) 1219-1224.
  67. -J. Cho, H.-M. Woo, K.-S. Kim, J.-W. Oh, Y.-J. Jeong, Journal of bioscience and bioengineering, 112 (2011) 535-540.
  68. Zuo, S. Li, Z. Guo, J. Zhang, C. Chen, Analytical chemistry, 76 (2004) 3536-3540.
  69. Roh, S.K. Jo, Journal of Chemical Technology & Biotechnology, 86 (2011) 1475-1479.
  70. Zhu, X. Wang, L. Han, T. Chen, L. Wang, H. Li, S. Li, L. He, X. Fu, S. Chen, medRxiv, (2020).
  71. Sanjaya, A. Ranzoni, J. Hung, M.A. Blaskovich, D. Watterson, P.R. Young, M.A. Cooper, Analytica Chimica Acta, (2020).
  72. Lee, P. Wang, M.A. Gaston, A.A. Weiss, P. Zhang, Plasmonics-based detection of virus using sialic acid functionalized gold nanoparticles, Biosensors and Biodetection, Springer2017, pp. 109-116.
  73. V.T. Nguyen, T.D. Dao, T.T.T. Trinh, D.-Y. Choi, S.-T. Yu, H. Park, S.-J. Yeo, Biosensors and Bioelectronics, 155 (2020) 112090.
  74. Zhong, E.L. Rosch, T. Viereck, M. Schilling, F. Ludwig, ACS sensors, 6 (2021) 976-984.
  75. Pramanik, Y. Gao, S. Patibandla, D. Mitra, M.G. McCandless, L.A. Fassero, K. Gates, R. Tandon, P.C. Ray, Nanoscale Advances, 3 (2021) 1588-1596.
  76. Wu, Q. Yu, Y. Joung, C.S. Jeon, S. Lee, S.H. Pyun, S.-W. Joo, L. Chen, J. Choo, Analytical Chemistry, (2023).
  77. Liu, T. Xie, X. Pei, S. Li, Y. He, Y. Tong, G. Liu, Sensors and Actuators B: Chemical, 377 (2023) 133009.
  78. Li, L. Rothberg, Proceedings of the National Academy of Sciences, 101 (2004) 14036-14039.
  79. M. Shawky, D. Bald, H.M. Azzazy, Clinical biochemistry, 43 (2010) 1163-1168.
  80. Tang, C.A. Hapip, B. Liu, C.T. Fang, Journal of clinical virology, 36 (2006) 177-182.
  81. Zhao, H. Cui, W. Song, X. Ru, W. Zhou, X. Yu, bioRxiv, (2020).
  82. Kim, M.J. Biondi, J.J. Feld, W.C. Chan, ACS nano, 10 (2016) 4742-4753.
  83. P. Wong, S. Othman, Y.L. Lau, S. Radu, H.Y. Chee, Journal of applied microbiology, 124 (2018) 626-643.
Chemical Review and Letters
Volume 6, Issue 3 - Serial Number 3
Autumn 2023
Pages 327-339

  • Receive Date 27 August 2023
  • Revise Date 17 September 2023
  • Accept Date 17 September 2023

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