Recent advances in the synthesis of pyrazolo[1,2-b]phthalazines

Document Type : Review Article

Author

Department of Chemistry, Firoozabad Branch, Islamic Azad University, Firoozabad, Iran

Abstract

The remarkable ability of pyrazolo[1,2-b]phthalazines as a nitrogen-containing heterocycles with fused scaffold of bridgehead hydrazine and pyrazole moieties have generated substantial interest in the pharmaceutical industry and in the diversified field of synthetic chemistry. The present mini-review focuses on current progress in the synthesis of 1H-pyrazolo[1,2‑b]phthalazine-5,10-dione derivatives using multi-component reaction of phthalhydrazide, aldehyde and malononitrile and covers publications from 2015 up to now.

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