Piperidine is a heterocyclic chemical molecule that is forming by hydrogenating pyridine. In natural and pharmaceutically active drugs, the piperidine ring is an essential molecular component. Several crystal structures of piperidine-4-ones and their derivatives are reported for their medicinal value. While several methods of piperidin-4-one crystallization have been developed to obtain a crystal structure, novel approaches are still needed. A review of the synthesis and crystallization procedure of piperidin-4-ones and its derivatives is outlined in this review paper.
Ramalingam, A. (2021). Synthesis and crystallization procedure of piperidin-4-one and its derivatives: An update. Chemical Review and Letters, 4(4), 192-199. doi: 10.22034/crl.2021.278234.1105
MLA
Arulraj Ramalingam. "Synthesis and crystallization procedure of piperidin-4-one and its derivatives: An update". Chemical Review and Letters, 4, 4, 2021, 192-199. doi: 10.22034/crl.2021.278234.1105
HARVARD
Ramalingam, A. (2021). 'Synthesis and crystallization procedure of piperidin-4-one and its derivatives: An update', Chemical Review and Letters, 4(4), pp. 192-199. doi: 10.22034/crl.2021.278234.1105
VANCOUVER
Ramalingam, A. Synthesis and crystallization procedure of piperidin-4-one and its derivatives: An update. Chemical Review and Letters, 2021; 4(4): 192-199. doi: 10.22034/crl.2021.278234.1105