%0 Journal Article %T Efficient and environmentally sustainable domino protocol for the synthesis of diversified dispiroheterocycles using 1-Butyl-3-methylimidazolium bromide [bmim]Br %J Chemical Review and Letters %I Eurasian Science Society (ESS) %Z 2676-7279 %A Gill, Charansingh H. %A Kulkarni, Makrand V. %A Jadhav, Chetan K. %A Nipate, Amol S. %A Magar, Bhausaheb K. %D 2021 %\ 05/01/2021 %V 4 %N 3 %P 153-163 %! Efficient and environmentally sustainable domino protocol for the synthesis of diversified dispiroheterocycles using 1-Butyl-3-methylimidazolium bromide [bmim]Br %K Multicomponent reaction %K Catalysis %K Dispiroheterocycles %K [bmim]Br %K Ionic Liquid %R 10.22034/crl.2021.278900.1107 %X An environmentally benign, simple, and efficient procedure has been developed for the construct of some symmetrical dispiroheterocycles derivatives by the reaction of the variety of 6-amino-2-thiouracil/6-aminouracil /2-amino-1,3,4-thiadiazole, isatins and p-toluidine in the presence of 1-Butyl-3-methylimidazolium bromide ([bmim]Br) as a solvent as well as catalyst at room temperature. In this study, a variety of bis-spiro-indoline-chromenes, pyranopyranes, imidazo-pyridines, pyrido-pyrimidines and pyridines were obtained with excellent yields within short reaction time and without chromatographic separation. Furthermore, the green catalytic system can be recycled speciļ¬c times with no decreases in yields and reaction rates. %U https://www.chemrevlett.com/article_131779_d7778c6f6afb94aa363696f2f5007564.pdf