@article { author = {Farshbaf, Sepideh and Sreerama, Lakshmaiah and Khodayari, Torkan and Vessally, Esmail}, title = {Propargylic ureas as powerful and versatile building blocks in the synthesis of various key medicinal heterocyclic compounds}, journal = {Chemical Review and Letters}, volume = {1}, number = {2}, pages = {56-67}, year = {2018}, publisher = {Eurasian Science Society (ESS)}, issn = {2676-7279}, eissn = {2645-4947}, doi = {10.22034/crl.2018.85120}, abstract = {This review article is an attempt to highlight the most important contributions toward the synthesis of various nitrogen-containing heterocyclic compounds from corresponding propargylic ureas through regio- and chemoselective 5-exo-dig and 6-endo-dig modes of N- and O-cyclization reactions. The review is divided into three major sections. In the first section we only focus on 5-exo-dig N-cyclization fashion. In the second section 5-exo-dig O-cyclization is described. The third section is devoted to 6-endo-dig N- and O-cyclizations}, keywords = {propargylic ureas,5-exo-dig cyclization,6-endo-dig cyclization,Heterocyclic compounds}, url = {https://www.chemrevlett.com/article_85120.html}, eprint = {https://www.chemrevlett.com/article_85120_ef4cf113bd74db6b9faf21f5ffa5623f.pdf} }