p. 1−1
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p. 2−9
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Cultivated fishes are major protein and microelement sources for all sorts of people in Bangladesh due to its availability and affordability. Since heavy metals are persistent in the aquatic environment, these metals can accumulate in the food chain. Cultivated fishes containing heavy metals can cause a carcinogenic and non-carcinogenic risk to human as it biologically accumulates heavy metals from commercial feeds. This study was designed to access the content of heavy metals in the flesh of some cultivated fish species through consuming commercial fish feeds available in Bangladesh and potential health risk calculation for consumers due to intake daily. The concentration (mg/kg, dry weight) range of heavy metals like; Pb (4.56- 7.08), Cd (0.23- 1.28), Cr (4.00-7.08), Cu (11.23- 20.62), As (0.08- 0.34), Hg (0.05- 0.34) in selected commercial fish feeds and Pb (4.35-8.03), Cd (0.87- 1.35), Cr (4.71-8.98), Cu (14.00- 31.80), As (0.17- 0.28), Hg (0.08- 0.41) in fishes were accessed by inductive coupled plasma optical emission spectroscopy (ICP-OES). The recorded concentration value for selected metals in fish tissues and feeds were also compared with the safe limit proposed by World health organization (WHO, 1995), Food and Agricultural Organization (FAO, 1983), European Union (EU, 2001). This study also estimated the carcinogenic and non- carcinogenic risk due to daily consumption of these cultivated fishes for a certain age.]]>
p. 10−20
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p. 21−29
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p. 30−36
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TAN1 (49%)>TAN2 (47%). Therefore, the immobilized bacteria are having higher potentials for the treatment of the anions in the effluents.]]>
p. 43−53
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In this work, the interaction between Flutamide (FLU) anticancer drug with nucleobases such as cytosine, thymine, uracil, and adenine was studied by density functional theory (DFT) methods from a thermodynamic point of view. The Gibbs free energy (ΔG) and enthalpy (ΔH) of C-FLU, T-FLU, U-FLU and A-FLU complexes were computed and demonstrate that the stronger interaction between cytosine and FLU and the adsorption of the drug on the bases proceeds spontaneously. The negative value of ΔH indicates that the adsorption of FLU drug on the cytosine, thymine and uracil bases are exothermic, these results confirmed ΔE results. During the interaction of Flutamide drug with nucleobases, the energy levels of the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) were significantly changed. The values of the energy gap (Eg) reduced during the adsorption of the FLU drug onto bases which confirmed that the reactivity of the resulted complex increase upon adsorption. On the other hand, as a result of theoretical calculations, the values of the Eg for the Base-FLU structures in water solution are decreased in comparison to the corresponding values in the gas phase, indicating more the reactivity of the studied complexes in the aqueous medium.]]>
p. 54−65
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